Excitatory and inhibitory neurons in (barrel) cortex process information very differently. This is both a result of differences in their intrinsic biophysical properties, and of differences in their position in the network (i.e. the network connectivity). To investigate the differences in intrinsic properties and how they are influenced by dopamine, Niccolò Calcini and Ate Bijlsma use our new method for measuring information transfer in in-vitro experiments. They use the results for the development of both single-neurons and network models, to unravel the roles of inhibitory and excitatory neurons in cortical networks. Eva Koenders is modelling VC experiments to investigate the threshold behaviour of these neurons. Xuan Yan and is testing the effects of D2 agonist.
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